Same-day & weekend vets in Charleston, SC

As of November 11, 2026, 7 clinics in Charleston, SC see non-emergency pets same-day; 11 of the 11 listed clinics are open weekends. 4 are 24/7 emergency hospitals. 8 accept walk-ins.

Hours, walk-in rules and published exam fees come from each clinic's own site. Call before you drive.

Emergency signs? Go to a 24/7 ER now: trouble breathing, collapse, blue/gray gums, a long seizure, heavy bleeding, a toxin swallowed, or a male cat straining to pee. The 24/7 hospitals are at the bottom of the list. Full checklist: urgent care or ER?

"Open now" is computed in your browser from posted hours (America/New_York) and doesn't know about holidays. Clinics without itemized hours stay listed as "Hours unclear, call ahead." Call before you drive.

Urgent careSee hours

PawMed Veterinary Urgent Care - Charleston / West Ashley

1200 Sam Rittenburg Blvd B2, Charleston, SC 29407

Mon10am–10pm
Tue10am–10pm
Wed10am–10pm
Thu10am–10pm
Fri10am–10pm
Sat10am–10pm
Sun10am–10pm

Urgent care open 7 days a week, 10am-10pm.

Walk-ins Yes

How to go Walk-ins welcome (per pawmedvet.com).

Exam fee Not published

Source: https://www.pawmedvet.com/locations/charleston/ · checked November 11, 2026 · Report a correction

Urgent careSee hours

PawMed Veterinary Urgent Care - Carnes Crossroads / Summerville

102 Gosling Way Suites C and D, Summerville, SC 29486

Closed Tuesday-Thursday. The West Ashley PawMed is open 7 days.
Mon10am–10pm
TueClosed
WedClosed
ThuClosed
Fri10am–10pm
Sat10am–10pm
Sun10am–10pm

Open Fri-Mon 10am-10pm.

Walk-ins Yes

How to go Walk-ins welcome (per pawmedvet.com).

Exam fee Not published

Source: https://www.pawmedvet.com/locations/carnes-crossroads/ · checked November 11, 2026 · Report a correction

Urgent careSee hours

AcutePet Urgent Care Summerville

143 Berkeley Circle, Unit 102, Summerville, SC 29483

Mon10am–10pm
Tue10am–10pm
Wed10am–10pm
Thu10am–10pm
Fri10am–10pm
Sat10am–10pm
Sun10am–10pm

Open 7 days, 10am-10pm. Holiday hours may vary. Dogs and cats; no strays or wildlife.

Walk-ins Yes

How to go Walk-ins welcome 7 days a week; same-day appointments can also be booked online or by phone.

Exam fee Not published

Source: https://acutepeturgentcare.com/locations/summerville/ · checked November 11, 2026 · Report a correction

Urgent careSee hours

AcutePet Urgent Care Mount Pleasant

966 Houston Northcutt Blvd, Suite E, Mount Pleasant, SC 29464

Closed Tuesday-Thursday.
Mon10am–10pm
TueClosed
WedClosed
ThuClosed
Fri10am–10pm
Sat10am–10pm
Sun10am–10pm

Open Fri-Mon 10am-10pm. Holiday hours may vary. Dogs and cats only.

Walk-ins Not published

How to go Same-day appointments; book online or call ahead. AcutePet's site says walk-ins are welcome at its Summerville location, but doesn't say whether this one takes them.

Exam fee Not published

Source: https://acutepeturgentcare.com/locations/mount-pleasant/ · checked November 11, 2026 · Report a correction

Urgent careSee hours

Charleston Veterinary Urgent Care

3163 W Montague Ave, North Charleston, SC 29418

Closed Tuesday-Thursday.
Mon9am–9pm
TueClosed
WedClosed
ThuClosed
Fri9am–9pm
Sat9am–9pm
Sun9am–9pm

Open Fri-Mon 9am-9pm. Urgent care only, so no vaccines or routine wellness.

Walk-ins Yes

How to go No appointment needed and walk-ins welcome. You can also check in online or call to ask about wait times.

Exam fee Not published

Source: https://charlestonveterinaryurgentcare.com/ · checked November 11, 2026 · Report a correction

Same-daySee hours

James Island Veterinary Hospital

756 Folly Rd, Charleston, SC 29412

Closed Sundays.
Mon7am–10pm
Tue7am–10pm
Wed7am–10pm
Thu7am–10pm
Fri7am–10pm
Sat7am–10pm
SunClosed

Full-service hospital that handles urgent cases during business hours, Mon-Sat 7am-10pm.

Walk-ins Not published

How to go Appointments strongly recommended, but the site says they'll always make time for urgent cases. Call ahead.

Exam fee $75 (Urgent Care Exam is $75 when you call ahead before visiting.)

Source: https://jamesislandvet.com/urgent-care/ · checked November 11, 2026 · Report a correction

Same-daySee hours

Daniel Island Animal Hospital

291 Seven Farms Dr, Suite 103, Daniel Island, SC 29492

Closed Sundays; Saturday only 8:30am-12:30pm.
Mon8am–6pm
Tue8am–6pm
Wed8am–6pm
Thu8am–6pm
Fri8am–6pm
Sat8:30am–12:30pm
SunClosed

Holds same-day sick and urgent slots every day. If those are full, they'll refer you to an urgent care or ER partner. A current rabies vaccine is required.

Walk-ins No

How to go Appointments only. Call 843-881-7228 to ask for a same-day sick slot.

Exam fee Not published

Source: https://danielislandvet.com/vet-hospital-policies · checked November 11, 2026 · Report a correction

24/7 ERSee hours

Charleston Veterinary Referral Center (24/7 ER)

3484 Shelby Ray Ct, Charleston, SC 29414

Hours Open 24 hours, 7 days

Emergency and specialty hospital, open 24/7/365 including holidays. No referral needed.

Walk-ins Yes

How to go No need to call first, but calling ahead helps them prepare. Phone triage with a nurse is free.

Exam fee Not published

Source: https://www.charlestonvrc.com/emergency · checked November 11, 2026 · Report a correction

24/7 ERSee hours

VEG ER for Pets Mount Pleasant (24/7 ER)

2183 N Hwy 17, Mount Pleasant, SC 29466

Hours Open 24 hours, 7 days

Open 24/7, including holidays. Also triages urgent issues like vomiting, limping, wounds, and ear or eye problems. Sees dogs, cats, birds, and exotics.

Walk-ins Yes

How to go Walk-in only; no appointments needed or taken. Calling first is recommended.

Exam fee Not published

Source: https://www.veg.com/locations/south-carolina/mount-pleasant · checked November 11, 2026 · Report a correction

Questions about vets in Charleston

Which vets in Charleston are open Sunday?

As of November 11, 2026, these listed clinics post Sunday hours: PawMed Veterinary Urgent Care - Charleston / West Ashley, PawMed Veterinary Urgent Care - Carnes Crossroads / Summerville, AcutePet Urgent Care Summerville, AcutePet Urgent Care Mount Pleasant, Charleston Veterinary Urgent Care, Charleston Veterinary Referral Center (24/7 ER), BluePearl Pet Hospital Mount Pleasant (24/7 ER), BluePearl Pet Hospital Summerville (24/7 ER), and VEG ER for Pets Mount Pleasant (24/7 ER). Other listed clinics are closed Sunday or have not published Sunday hours; see each card.

Is there a walk-in vet in Charleston?

Yes. As of November 11, 2026, these listed clinics say they accept walk-ins: PawMed Veterinary Urgent Care - Charleston / West Ashley, PawMed Veterinary Urgent Care - Carnes Crossroads / Summerville, AcutePet Urgent Care Summerville, Charleston Veterinary Urgent Care, Charleston Veterinary Referral Center (24/7 ER), BluePearl Pet Hospital Mount Pleasant (24/7 ER), BluePearl Pet Hospital Summerville (24/7 ER), and VEG ER for Pets Mount Pleasant (24/7 ER). Call ahead, because a clinic may still be full. Daniel Island Animal Hospital does not accept walk-ins, according to their own sites. Clinics that have not published a walk-in policy are marked “not published” on their cards.

What's the difference between urgent care and an ER?

Urgent care and same-day clinics are for a sick pet that isn't in danger, such as vomiting, limping, small wounds, ear or eye problems, or a pet that's “off” but alert. A 24/7 emergency hospital is for trouble breathing, collapse, blue/gray gums, a long seizure, heavy bleeding, a toxin swallowed, or a male cat straining to pee. Many urgent-care clinics close overnight, and ERs see the sickest pets first, so minor cases may wait. On this page, Charleston Veterinary Referral Center (24/7 ER), BluePearl Pet Hospital Mount Pleasant (24/7 ER), BluePearl Pet Hospital Summerville (24/7 ER), and VEG ER for Pets Mount Pleasant (24/7 ER) post 24/7 hours and are listed at the bottom. There is a full printable checklist at https://vetsopentoday.com/urgent-or-er.html.

Are there 24/7 emergency vets in Charleston?

Yes. As of November 11, 2026, Charleston Veterinary Referral Center (24/7 ER), BluePearl Pet Hospital Mount Pleasant (24/7 ER), BluePearl Pet Hospital Summerville (24/7 ER), and VEG ER for Pets Mount Pleasant (24/7 ER) post 24/7 emergency hours.